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Search Result

Search Results for " ku70 "

Targets

DNA-PK Others

5

Compounds

3

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T13017 STL127705 Compound L,7-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]-3-(3-fluorophenyl)pyrimido[4,5-d]pyrimidine-2,4(1H,3H)-dione DNA-PK , Others
STL127705 (Compound L) is a potent Ku 70/80 heterodimer protein inhibitor and inhibits Ku70/80-DNA interaction with IC50 of 3.5 μM. STL127705 inhibits the activation of Ku-dependent DNA-PKCS kinase with IC50 of 2.5 μM.
T6960L PU-H71 HCl PU-H71 HCl(873436-91-0 Free base),Zelavespib HCl HSP , DNA/RNA Synthesis
PU-H71 HCl (Zelavespib HCl) is a novel Hsp90 inhibitor, a novel purine-based analog, and a radiosensitizer that may be a promising agent for CIRT. PU-H71 HCL shows antitumor activity in many preclinical models of maligna...
T61633 DNA-PK-IN-2
DNA-PK-IN-2 is a highly effective inhibitor of DNA-dependent protein kinase (DNA-PK), which is a complex enzyme composed of Ku70/Ku80 heterodimer and DNA-PK catalytic subunit (DNA-PKcs). With its potential applications i...
T74501 NHEJ inhibitor-1
NHEJ Inhibitor-1 (Compound C2), a trifunctional Pt(II) complex, mitigates non-homologous end joining (NHEJ)/homologous recombination (HR)-related double strand break (DSB) repairs, combating Cisplatin resistance in non-s...
T62648 DNA-PK-IN-1
DNA-PK-IN-1 is a potent inhibitor of DNA-PK. DNA-PK-IN-1 has potential for cancer disease research.

Recombinant Proteins

Species：
Human (3)
Expression System：
HEK293 Cells (2)
Baculovirus Insect Cells (1)
Tag：
C-6xHis (1)
C-hFc-6xHis (1)
His (1)
Cat No. Product Name Species Expression System
TMPY-02287 Ku70 & Ku80 Heterodimer Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
X-ray repair cross-complementing protein 5, also known as 86 kDa subunit of Ku antigen, ATP-dependent DNA helicase 2 subunit 2, ATP-dependent DNA helicase II 8 kDa subunit, CTC box-binding factor 85 kDa subunit, DNA repa...
TMPJ-00278 Clusterin Protein, Human, Recombinant (hFc & His) Human HEK293 Cells
Clusterin Protein, Human, Recombinant (hFc & His) is expressed in HEK293 mammalian cells with C-Fc-6xHis tag. The predicted molecular weight is (33-45) and (60-85) KDa and the accession number is P10909.
TMPJ-00279 Clusterin Protein, Human, Recombinant (His) Human HEK293 Cells
Clusterin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 28-40 KDa and the accession number is P10909.
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